During the past few years, the benefits of soy milk and soy foods have become widely debated. All it takes is a search online to discover some intelligent arguments and clinical studies concerning the potential health dangers that are present in the soy products that families regularly consume.
Thankfully, more and more independent research has been done regarding the dangers of soy, and what it’s revealed should scare you.
Phytoestrogens
Soy is higher in phytoestrogens than just about any other food source. Phytoestrogens are plant-based estrogens that mimic estrogen in our bodies. In recent years, you may have read about studies which indicate phytoestrogens are good for you. But ask yourself, who funded those studies? The soy industry, that’s who. Independent research has clearly shown that consuming phytoestrogens is downright dangerous for the human body.
It’s only common sense. No one argues, for example, that a leading cause of breast cancer, endometriosis, uterine fibroids, infertility, and low libido is unopposed estrogen, or estrogen dominance. Why, then, would anyone argue that we should consume more of a food high in estrogen?
An infant taking the recommended amount of soy formula is consuming a hormone load equivalent of 4 birth control pills a day! Is it any wonder we’ve seen such a dramatic rise in precocious puberty with young girls starting their periods at 6 and 7?
Goitrogenic
Soy will destroy your thyroid. Many foods are goitrogenic (thyroid suppressing), but soy is king of them all. Goitrogens work by preventing your thyroid from getting the necessary amount of iodine. Friends, I believe this is what happened to Oprah’s thyroid. She pushed soy for years, featured it in everyone one of her “healthy” diets, and it destroyed her thyroid. If your thyroid fails, what happens? You gain weight. You have a harder time regulating your moods. You get colder more easily. You’re more easily fatigued. You demonstrate an inability to concentrate and remember details. The list goes on. You simply don’t want to mess with your thyroid.
Phytates
Phytates are enzyme-inhibitors that block mineral absorption in human digestive tract. They are naturally present in all grains, seeds, nuts, and legumes (which is why everyone should read this primer on how to eat grains, if you eat them at all.) But soy is so high in phytates that it’s almost impossible to get rid of them. Simply soaking soy overnight in an acidic medium won’t do the trick. Soy must be fermented in order to be digestible to humans. That means that if you eat soy at all, you should stick to fermented soy products like miso, tempeh, natto, or a naturally fermented soy sauce (tamari).
Trypsin inhibitors
Finally soy is rich in trypsin inhibitors. Trypsin is a digestive enzyme we need to properly digest protein. Without enough trypsin, you’ll experience many digestive problems including stomach cramps, diarrhea, and bleeding. You’ll also be leaving yourself open to future problems with your pancreas.
Debunking The Asian Soy Myth
But, people say, what about Asians? They eat soy every day, and they’re so healthy!
In this article by Nina Planck, she writes:
Soy farming started around 1100 BC in China, where it was used to build soil fertility and feed animals. Soy beans were not considered fit for humans until the Chinese learned to ferment them, which makes them digestible. Asian diets now include fermented soy beans in the form of natto, miso, tamari, and tempeh.
Soy producers want you to eat more soy — more than the Asians eat, and more than is good for you. The Japanese and Chinese eat 10 grams of soy per day — about two teaspoons. Yet a soy manufacturer recommends Americans eat ten times what the Japanese eat — 100 grams of soy protein per day. In The Soy Zone, Barry Sears recommends a daily diet of a minimum of 50 grams of soy, and up to 75 grams for women and 100 grams for men.
It’s like red wine: a glass or two a day may be good for you; a bottle or two every day rots your liver.
Did you catch that? Asians only eat 2 teaspoons of soy a day, usually as a condiment, and it’s highly fermented! Fermentation takes care of many of the dangers of soy. Plus, the typical Asian will also consume soy with mineral-rich and nutrient-dense foods such as fish broth (naturally high in iodine & other minerals which support the thyroid).
So, Is Soy Bad For You?
The short answer? YES! Let’s be clear on the recent history of soy. The soybean was a modest and unpopular crop until food manufacturers intent on creating cheap vegetable oils convinced the U.S. government to start subsidizing it. The soy was turned into oil, and the industry was left with an industrial waste product. Then somebody had a brilliant idea:
Let’s take this industrial waste product full of toxins and carcinogens — isolated soy protein — and turn it into food that people will eat!
Soy foods were born. From Nina Planck’s article:
The FDA refused to approve isolated soy protein as a safe food additive with the designation “Generally Recognized as Safe.”
Agribusiness giant Archer Daniels Midland withdrew its application for the coveted GRAS status for soy protein, after an outcry from scientists about the toxins and carcinogens that come with it. They can still put soy protein in your food, but they have to get pre-market approval for every product.
Isolated soy protein is no health food. But we don’t eat soy protein with a spoon. How do we eat it? It is the main ingredient in soy burgers, ice cream, milk shakes, and fake cheese. These soy protein products are phony foods — but they must look like the real foods they imitate. So the soy industry transforms a small yellow soy bean into something resembling a hamburger. They make soy “milk” and “ice cream” white and creamy.
The other ingredients in these foods are no better for you than the soy protein that goes into them. Soy milk, for example, is simply a cocktail of soy protein, sugar, and vegetable oil. The “natural” MSG formed in soy processing is already bad for you, but even more MSG, and more flavorings, are added. Imitation foods need a lot of help to be tasty. Many savory soy foods are loaded with additives to give them the flavor of the real foods they mimic. Most imitation meat, for example, contains man-made MSG, which causes migraines and is associated with brain cancer.
Soy and the Brain
"Tofu Shrinks Brain!" No science fiction scenario, this sobering soybean revelation is for real. But how did the "poster bean" of the ’90s go wrong? Apparently, in many ways--none of which bode well for the brain.
In a major ongoing study involving 3,734 elderly Japanese-American men, those who ate the most tofu during midlife had up to 2.4 times the risk of later developing Alzheimer’s disease. As part of the three-decade long Honolulu-Asia Aging Study, 27 foods and drinks were correlated with participants’ health. Men who consumed tofu at least twice weekly had more cognitive impairment than those who rarely or never ate the soybean curd.
"The test results were about equivalent to what they would have been if they were five years older," said lead researcher Dr. Lon R. White from the Hawaii Center for Health Research. For the guys who ate no tofu, however, they tested as though they were five years younger.
What’s more, higher midlife tofu consumption was also associated with low brain weight. Brain atrophy was assessed in 574 men using MRI results and in 290 men using autopsy information. Shrinkage occurs naturally with age, but for the men who had consumed more tofu, White said "their brains seemed to be showing an exaggeration of the usual patterns we see in aging."
Phytoestrogens--Soy Self Defense
Tofu and other soybean foods contain isoflavones, three-ringed molecules bearing a structural resemblance to mammalian steroidal hormones. White and his fellow researchers speculate that soy’s estrogen-like compounds (phytoestrogens) might compete with the body’s natural estrogens for estrogen receptors in brain cells.
Plants have evolved many different strategies to protect themselves from predators. Some have thorns or spines, while others smell bad, taste bad, or poison animals that eat them. Some plants took a different route, using birth control as a way to counter the critters who were wont to munch.
Plants such as soy are making oral contraceptives to defend themselves, says Claude Hughes, Ph.D., a neuroendocrinologist at Cedars-Sinai Medical Center. They evolved compounds that mimic natural estrogen. These phytoestrogens can interfere with the mammalian hormones involved in reproduction and growth--a strategy to reduce the number and size of predators.
Toxicologists Concerned about Soy’s Health Risks
The soy industry says that White’s study only shows an association between tofu consumption and brain aging, but does not prove cause and effect. On the other hand, soy experts at the National Center for Toxicological Research, Daniel Sheehan, Ph.D., and Daniel Doerge, Ph.D., consider this tofu study very important. "It is one of the more robust, well-designed prospective epidemiological studies generally available. . . We rarely have such power in human studies, as well as a potential mechanism."
In a 1999 letter to the FDA (and on the ABC News program 20/20), the two toxicologists expressed their opposition to the agency’s health claims for soy, saying the Honolulu study "provides evidence that soy (tofu) phytoestrogens cause vascular dementia. Given that estrogens are important for maintenance of brain function in women; that the male brain contains aromatase, the enzyme that converts testosterone to estradiol; and that isoflavones inhibit this enzymatic activity, there is a mechanistic basis for the human findings."
Although estrogen’s role in the central nervous system is not well understood, White notes that "a growing body of information suggests that estrogens may be needed for optimal repair and replacement of neural structures eroded with aging."
One link to the puzzle may involve calcium-binding proteins, which are associated with protection against neurodegenerative diseases. In recent animal studies at Brigham Young University’s Neuroscience Center, researchers found that consumption of phytoestrogens via a soy diet for a relatively short interval can significantly elevate phytoestrogen levels in the brain and decrease brain calcium-binding proteins.
Concerns About Giving Soy to Infants
The most serious problem with soy may be its use in infant formulas. "The amount of phytoestrogens that are in a day’s worth of soy infant formula equals 5 birth control pills," says Mike Fitzpatrick, a New Zealand toxicologist. Fitzpatrick and other scientists believe that infant exposure to high amounts of phytoestrogens is associated with early puberty in girls and retarded physical maturation in boys.
A study reported in The Lancet found that the "daily exposure of infants to isoflavones in soy infant-formulas is 6-11 fold higher on a bodyweight basis than the dose that has hormonal effects in adults consuming soy foods." (This dose, equivalent to two glasses of soy milk per day, was enough to change menstrual patterns in women.6 In the blood of infants tested, concentrations of isoflavones were 13,000-22,000 times higher than natural estrogen concentrations in early life. )
Soy Interferes with Enzymes
While soybeans are relatively high in protein compared to other legumes, they are a poor source of protein because other proteins found in soybeans act as potent enzyme inhibitors. These "anti-nutrients" block the action of trypsin and other enzymes needed for protein digestion. Trypsin inhibitors are large, tightly folded proteins that are not completely deactivated during ordinary cooking and can reduce protein digestion. Therefore, soy consumption may lead to chronic deficiencies in amino acid uptake.
Soy’s ability to interfere with enzymes and amino acids may have direct consequence for the brain. As White and his colleagues suggest, "isoflavones in tofu and other soyfoods might exert their influence through interference with tyrosine kinase-dependent mechanisms required for optimal hippocampal function, structure and plasticity."
High amounts of protein tyrosine kinases are found in the hippocampus, a brain region involved with learning and memory. One of soy’s primary isoflavones, genistein, has been shown to inhibit tyrosine kinase in the hippocampus, where it blocked "long-term potentiation," a mechanism of memory formation.
Tyrosine, Dopamine, and Parkinson’s Disease
The brain uses the amino acids tyrosine or phenylalanine to synthesize the key neurotransmitters dopamine and norepinephrine, brain chemicals that promote alertness and activity. Dopamine is crucial to fine muscle coordination. People whose hands tremble from Parkinson’s disease have a diminished ability to synthesize dopamine. An increased incidence of depression and other mood disorders are associated with low levels of dopamine and norepinephrine. Also, the current scientific consensus on attention-deficit disorder points to a dopamine imbalance.
Soy has been shown to affect tyrosine hydroxylase activity in animals, causing the utilization rate of dopamine to be "profoundly disturbed." When soy lecithin supplements were given throughout perinatal development, they reduced activity in the cerebral cortex and "altered synaptic characteristics in a manner consistent with disturbances in neural function."
Researchers at Sweden’s Karolinska Institute and at the National Institutes of Health are finding a connection between tyrosine hydroxylase activity, thyroid hormone receptors, and depleted dopamine levels in the brain--particularly in the substantia nigra, a region associated with the movement difficulties characteristic of Parkinson’s disease.
Soy Affects the Brain via the Thyroid Gland
Tyrosine is crucial to the brain in another way. It’s needed for the body to make active thyroid hormones, which are a major physiological regulator of mammalian brain development. By affecting the rate of cell differentiation and gene expression, thyroid hormones regulate the growth and migration of neurons, including synaptic development and myelin formation in specific brain regions. Low blood levels of tyrosine are associated with an underactive thyroid gland.
It is well known that isoflavones in soy products can depress thyroid function, causing goiter (enlarged thyroid gland) and autoimmune thyroid disease. In the early 1960s, goiter and hypothyroidism were reported in infants fed soybean diets.14 Scientists at the National Center for Toxicological Research showed that the soy isoflavones genistein and daidzein "inhibit thyroid peroxidase-catalyzed reactions essential to thyroid hormone synthesis.
Japanese researchers studied effects on the thyroid from soybeans administered to healthy subjects. They reported that consumption of as little as 30 grams (two tablespoons) of soybeans per day for only one month resulted in a significant increase in thyroid stimulating hormone (TSH), which is produced by the brain’s pituitary gland when thyroid hormones are too low. Their findings suggested that "excessive soybean ingestion for a certain duration might suppress thyroid function and cause goiters in healthy people, especially elderly subjects."16
Thyroid Hormones and Fetal Brain Development
Thyroid alterations are among the most frequently encountered autoimmune conditions in children. Researchers at Cornell University Medical College showed that the "frequency of feedings with soy-based milk formulas in early life was significantly higher in children with autoimmune thyroid disease."17 In a previous study, they found that twice as many diabetic children had received soy formula in infancy as compared to non-diabetic children.
Recognizing the risk, Swiss health authorities recommend "very restrictive use" of soy for babies. In England and Australia, public health agencies tell parents to first seek advice from a doctor before giving their infants soy formula. The New Zealand Ministry of Health recommends that "Soy formula should only be used under the direction of a health professional for specific medical indications. . . Clinicians who are treating children with a soy-based infant formula for medical conditions should be aware of the potential interaction between soy infant formula and thyroid function."
Thyroid hormones exert their influence during discrete windows of time during development of the infant. Inappropriate hormone levels can have a devastating effect on the developing human brain, especially during the first 12 weeks of pregnancy when the fetus depends on the mother’s thyroid hormones for brain development. After that, both maternal and fetal thyroid hormone levels affect the central nervous system.
A 1999 study published in the New England Journal of Medicine showed that pregnant women with underactive thyroids were four times more likely to have children with low IQs if the disorder were left untreated. The study found that 19 percent of the children born to mothers with thyroid deficiency had IQ scores of 85 or lower, compared with only 5 percent of those born to mothers without such problems.
Thyroid, Brain, and Environmental Toxins
Children exposed prenatally and during infancy to common environmental toxins like dioxin and polychlorinated biphenyls (PCBs) can suffer behavioral, learning, and memory problems because these chemicals may be disrupting the normal action of thyroid hormone.
Soybeans grown in the United States contain residues of the pesticide dieldrin, an organochlorine similar to DDT. Although both chemicals were banned in the 1970s, dieldrin still persists in soils and is absorbed through the roots. Today it is the most toxic residue found on domestic soybeans. In Silent Spring, Rachel Carson warned that dieldrin is nearly 50 times as poisonous as DDT. In addition to disrupting hormones, it can have long delayed neurological effects, ranging from loss of memory to mania. Chinese aphids were recently discovered in fields scattered across Wisconsin, so increased pesticide applications are likely.
Combinations of insecticides, weed killers, and artificial fertilizers--even at low levels--have measurable detrimental effects on thyroid and other hormones as well as on the brain. EPA scientists now want to upgrade the commonly used herbicide, atrazine, to a "likely carcinogen." In animal tests, atrazine attaches to sites on the hypothalamus, a crucial brain region involved with regulating levels of stress and sex hormones.25
Individuals newly diagnosed with Parkinson’s disease were more than twice as likely to have been exposed to insecticides in their home, compared to those without the disease In September 2000, The Lancet reported that farmers and gardeners regularly exposed to pesticides may have more than five times the risk of developing mild cognitive dysfunction.
Soy formulas for infants can contain other neurotoxins: aluminum, cadmium, and fluoride. Studies found that aluminum concentrations in soy-based formulas were a 100-fold greater compared to human breast milk, while cadmium content was 8-15 times higher than in milk-based formulas. In an Australian study, the fluoride content of soy-based formulas ranged from 1.08 to 2.86 parts per million. The authors concluded that "prolonged consumption (beyond 12 months of age) of infant formula reconstituted with optimally-fluoridated water could result in excessive amounts of fluoride being ingested." A study of Connecticut children revealed that mild to moderate fluorosis was strongly associated with soy-based infant formula use.
In May 2000, Boston Physicians for Social Responsibility released their report, "The Toxic Threats to Child Development." In the section on neurotoxins, they concluded, "Studies in animals and human populations suggest that fluoride exposure, at levels that are experienced by a significant proportion of the population whose drinking water is fluoridated, may have adverse impacts on the developing brain."
Iodine versus Fluorine
The thyroid gland uses tyrosine and the natural element iodine to make thyroxine (T4), a thyroid hormone containing four iodine atoms. The other, much more biologically active thyroid hormone is tri-iodothyronine (T3), which has three iodine atoms. Lack of dietary iodine has long been identified as the problem in diminished thyroid hormone synthesis.
According to the International Council for the Control of Iodine Deficiency Disorders: "Iodine deficiency has been called the world’s major cause of preventable mental retardation. Its severity can vary from mild intellectual blunting to frank cretinism, a condition that includes gross mental retardation, deaf mutism, short stature, and various other defects. . . The damage to the developing brain results in individuals poorly equipped to fight disease, learn, work effectively, or reproduce satisfactorily."
This crucial role of iodine is another reason why the thyroid gland is especially vulnerable today. Canadian researcher Andreas Schuld has documented more than 100 studies during the last 70 years that demonstrate adverse effects of fluoride on the thyroid gland. Schuld says, "Fluorine, being the strongest in the group of halogens, will seriously interfere with iodine and iodine synthesis, forcing more urinary elimination of ingested iodine as fluoride ingestion or absorption increases.
"Soy Inhibits Zinc Absorption
The high phytic-acid content in soy may also have adverse effects on brain function. Phytic acid is an organic acid present in the outer portion of all seeds which blocks the uptake of essential minerals in the intestinal tract: calcium, magnesium, iron, and especially zinc. Soybeans have very high levels of a form of phytic acid that is particularly difficult to neutralize and which interferes with zinc absorption more completely than with other minerals.
The soy industry acknowledges the problem with the admission that while "one-half cup of cooked soybeans contains one mg of zinc
. . . zinc is poorly absorbed from soyfoods." As for iron, "both phytate and soy protein reduce iron absorption so that the iron in soyfoods is generally poorly absorbed."
According to unpublished documents, researchers testing soy formula found that it caused negative zinc balance in every infant to whom it was given. Even when the diets were additionally supplemented with zinc, there was a strong correlation between phytate content in formula and poor growth.
Zinc and the Brain
Relatively high levels of zinc are found in the brain, especially the hippocampus. Zinc plays an important role in the transmission of the nerve impulse between brain cells. Deficiency of zinc during pregnancy and lactation has been shown to be related to many congenital abnormalities of the nervous system in offspring. In children, "insufficient levels of zinc have been associated with lowered learning ability, apathy, lethargy, and mental retardation."
The USDA references a study of 372 Chinese school children with very low levels of zinc in their bodies. The children who received zinc supplements had the most improved performance--especially in perception, memory, reasoning, and psychomotor skills such as eye-hand coordination. Three earlier studies with adults also showed that changes in zinc intake affected cognitive function.
New research has identified a specific contingent of neurons, called "zinc-containing" neurons, which are found almost exclusively in the forebrain, where in mammals they have evolved into a "complex and elaborate associational network that interconnects most of the cerebral cortices and limbic structures." This suggests the importance of zinc in the normal and pathological processes of the cerebral cortex. Furthermore, age-related tissue zinc deficiency may contribute to brain cell death in Alzheimer’s dementia.
Not a Good Idea
High levels of phytoestrogens and zinc-blocking phytic acid, plus additional neurotoxic compounds such as dieldrin, aluminum, fluoride and cadmium combine in soy to yield a veritable witches’ brew that can have adverse effects on the brain during development and throughout life.
Unfortunately, many American are now consuming soy foods in high amounts as infant formula, soy milk and tofu-based products, usually as a substitute for nourishing animal foods. In Asia, soy is consumed in small amounts as a fermented condiment and not as a substitute for animal foods.
Asians recognize the need for "brain foods" like eggs and fish and realize that large amounts of soy can cause thyroid problems and inhibit growth. They know that for optimum mental function, soy foods are not a good idea.
But what if all you've read about soy is nothing but a multi-million dollar marketing strategy based on scanty facts, half-truths and lies?
Most people remain unaware that soy is known to contain an array of potent chemical toxins. The modern manufacturing processes of high-profit industries make no effort to remove these potent toxins. High levels of phytic acid, trypsin inhibitors, toxic lysinoalanine and highly carcinogenic nitrosamines are all present in soy products.
Phytoestrogens that disrupt endocrine function and are potent antithyroid agents are present in vast quantities in soy, including the potentially devastating isoflavone Genistein. Infants exclusively fed soy-based formula have 13,000 to 22,000 times more estrogen compounds in their blood than babies fed milk-based formula, the estrogenic equivalent of at least five birth control pills per day. Premature development of girls has been linked to the use of soy formula, as has the underdevelopment of males. Infant soy formula has been linked to autoimmune thyroid disease.
Soy is linked to infertility, breast cancer, hypothyroidism, thyroid cancer, and many other disorders.
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True Health, the Magazine of Carotec Inc., Naples, Florida. May/June 2004.
"Imagine drugs that are known, by years of scientific documentation, to be both carcinogenic and to also cause DNA and chromosome damage being prescribed and administered through the food supply to populations of many countries around the world without the knowledge or consent of the individuals consuming these foods ... with no way to track dosage, individual reactions, or harmful side-effects ... and without any concern for some people’s increased vulnerability to these drugs, such as cancer patients. It sounds crazy, but that is exactly what is happening around the world when Soy is added to our food supply. Soy contains the scientifically documented carcinogenic and DNA damaging and chromosome damaging natural chemicals genistein and daidzein."
How could anyone get away with this?
The soy industry is one of the world's most wealthy and powerful multi-billion dollar industries.
"Despite an impressive array of scientific evidence that soy is not a fit food for man nor beast, the soy marketing mastodon has marched through the American market like Sherman through Georgia - and likely doing about as much damage as Sherman's Union Army did. In our opinion the widespread use of non-fermented soy is part of the chronic disease problem since soy is known to wreak havoc with the human thyroid and other hormone systems."
"(Soyfoods) are not nutrients. They are drugs."
Dr. L. White, Honolulu Aging Study.
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